The difference of material and production process between infusion set and blood transfusion set
I. Material Differences
Infusion Sets:
The most common material used in infusion sets is polyvinyl chloride (PVC). However, PVC materials often incorporate plasticizers (e.g., DEHP) during production, which may adsorb certain medications, reducing the effective drug concentration. Additionally, DEHP poses potential toxicity risks to humans.
To address PVC-related issues, newer materials such as ultra-low-density polyethylene (PE), thermoplastic polyolefin elastomer (TPE), and polyurethane (TPU) have been introduced in infusion sets.
Blood Transfusion Sets:
Currently, 90% of domestically produced blood transfusion tubing and funnels use PVC. This material exhibits strong adsorption properties for alcohol-soluble and lipid-soluble drugs, potentially compromising prescription accuracy.
The filter pore size in blood transfusion sets is relatively large, making them prone to blockage by microaggregates (e.g., platelets and leukocytes) in blood cells, thereby reducing effective filtration area.
II. Production Process Differences
Infusion Sets:
The production process for infusion sets includes injection molding, assembly, and sterilization.
During injection molding, parameters such as temperature, pressure, and injection speed must be tightly controlled to ensure product appearance and dimensional accuracy.
Assembly requires rigorous inspection and leakage testing to guarantee seal integrity at connection points.
Sterilization is critical for ensuring aseptic conditions, requiring appropriate sterilization methods and strict control of sterilant dosage and exposure time.
Blood Transfusion Sets:
The production process for blood transfusion sets involves raw material procurement, high-frequency heat welding of components, quality inspection, packaging, sterilization, and distribution.
Similar to infusion sets, blood transfusion sets require strict parameter and quality control throughout production to ensure safety and reliability.
Notably, blood transfusion sets must withstand higher pressures and larger flow rates, leading to more complex and stringent production requirements.
